Includes bibliographical references and index.
|Statement||Laura S. Peale (editor).|
|Contributions||Peale, Laura S.|
|LC Classifications||RC268.42 .P76 2005|
|The Physical Object|
|LC Control Number||2005011339|
This book gives a good feel for the human side of basic research in biology. At the same time it acts as a good introduction to the role of genes in cancer. It is disappointing to see how wide is the gap between knowledge of the DNA failures and how these genes control the processes in the by: The study of oncogenes and tumor suppressor genes continues to be a fast-moving area of science. This authoritative text provides a conceptual framework which allows students and professionals to understand this complex field. It also serves as a comprehensive reference for scientists engaged in oncogene research. The second edition of this text details major advances and developments in the. Recent Progress in Hormone Research, Volume 48 provides information pertinent to endocrine research dealing with all aspects of biological organization. This book covers a variety of topics, including differentiation of the embryo, development and growth at puberty, maintenance of adult well-being, and aging. 1. Gan To Kagaku Ryoho. Jun;14(6 Pt 2) [Recent progress in oncogene studies]. [Article in Japanese] Toyoshima K. Oncogene studies have become an area of general interest in the field of cancer research following the identification of the cellular counterparts of viral oncogenes.
Activation of proto-oncogenes to oncogenes results in a gain of function and may be quantitative (an increase in the production of an unaltered product) or qualitative (the production of a modified product).As a result of these alterations, activated oncogenes induce abnormal cell proliferation and therefore tumor development. Quantitative forms of oncogene activation occur either by. LORETTA L.Y. TSE, JOHN K.C. CHAN, in Modern Surgical Pathology (Second Edition), MOLECULAR BIOLOGY. The RET proto-oncogene on chromosome 10q11 plays a key role in the genesis of medullary carcinoma. The RET gene, which has 21 exons, encodes a receptor tyrosine kinase with a cysteine-rich extramembrane domain, a transmembrane domain, and an intracellular tyrosine . Recent Progress of Life Science Technology in Japan discusses developments in cancer research technologies in Japan. In June an intra-cabinet panel of the Japanese Government drafted a year strategy for cancer control, recognizing the importance of this field of research. Partner profile for Oncogene Research Products at Get contact information and browse product offerings and application notes.
Part of the Progress in Cell Cycle Research book series (PCCR) Abstract The mos proto-oncogene-encoded serine/threonine protein kinase plays a key cell cycle-regulatory role during meiosis. Progress in Cancer Research Basic, molecular, epidemiologic, and clinical research are leading to improved cancer prevention, screening, and treatment. Decreasing cancer mortality death rates and increasing numbers of cancer survivors are important indicators of the progress we have made. Lung cancer cells driven by the KRAS oncogene, which is highlighted in purple. Credit: National Cancer Institute. NCI-funded researchers are working to advance our understanding of how to prevent, detect, and treat lung cancer. There has been a great deal of progress made, for scientists are identifying many different genetic alterations that can drive lung cancer growth. I've read the first () edition. This is a wonderful introduction to the molecular basis of oncogene structure and function. At this time () the edition may be a bit dated but still if you really want to clearly understand how oncogenes were discovered, this is a great book to do it with. Highly s: 2.